IIT - Molecular Neuroscience
Research Activity
   Last Update: 060920


The program of this Unit offers a comprehensive overview of the scientific and technological work envisaged at the San Raffaele Institute (HSR) in Neuroscience, with specific developments in drug identification and robotics. The groups have an established tradition of excellence, documented by patents and publications, widely recognized and appreciated at the international level. In addition, they have participated in the organization and operation of technological initiatives aimed at the generation of new research tools and the development of scientific results towards application. Therefore, their participation in the Unit does not change their activity but offers them the possibility to expand their perspectives. Collaborations with groups active in other Units and with groups destined to join the IIT in the near future are already going on. In the future we expect them to be further expanded by the participation of other groups, and also qualified by the increased technological potential and impact of the IIT enterprise.

In order to introduce the role that the HSR Unit intends to play in the IIT Network program let’s first briefly summarize a few important aspects of the HSR Scientific Research Institute (IRCCS). Collaboration among research groups in terms of both scientific and technological research is continuous and extremely fruitful. Along this line, HSR has developed advanced facilities in several important research fields, from protein sequencing to transgenic and knock-out mice; from in vivo imaging to microchip RNA analysis, that have proven of key importance not only for the advancement of the work but also for the widening of the technological know-how. In addition, the installment of the mega-computer Blue GeneP is expected to result in a real explosion of bioinformatics, with ensuing major and precious fall-out in all fields of bio-science and bio-technology. Finally, HSR includes a famous hospital, leader in the world in a number of important areas, including in particular medical neuroscience, where research is carried out at very high level. The vast opportunities offered by this environment, which so far have been essential for the development of the internal groups, including those of the HSR Unit, will now become open to the entire IIT network.

All the 7 groups of the HSR Unit have distinct scientific profiles, illustrated in detail in the following presentations. Groups 1, 2 and 5 have strong background in cellular neuroscience, oriented however to distinct technological and applicative developments; groups 3 and 4 have long and innovative experience in the field of innovative drug development; group 6 is specialist in fluorescence spectroscopy while group 7 is active in the contact area between neuroscience and robotics. All groups have research support from external sources for studies adjacent to, or coinciding with those of the IIT Unit. Therefore support to the studies presented in this document can be envisaged as a real co-funding. For the first few months the Unit will begin its activity in the laboratories already occupied by the participating groups. Soon, however, additional space, dedicated specifically to the IIT Unit, will be assigned in the new research building of the HSR area. We envisage this as an important step to strengthen our coordinate activity and to facilitate external collaborations. Finally, a new branch of the PhD School in Molecular Medicine, oriented specifically to Biotechnology of Neuroscience and sponsored by both the IIT and the Vita-Salute San Raffaele University has been recently opened for two 4year cycles. The Unit and the School will work in strict collaboration, assuring the students continuous contacts with IIT and introducing them to qualified research work oriented towards the synergistic combination of science and technology.